This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5mg/ml
Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Applications
WB - Quality tested
Description
RIG-1/DDX58(Retinoic acid-inducible gene 1 protein/ DEAD-box protein 58) is an RNA helicase that belongs to the DEAD/H box. Contains 2 CARD domains, a helicase ATP-binding domain and a helicase C-terminal domain. Predicted molecular weight approximately 107 kD. RIG-1 has an essential function in double-stranded RNA-induced innate antiviral responses. RIG-1 and MDA5 (melanoma differentiation-associated gene 5) are key intracellular receptors that sense intracellular viral infection and trigger a signal forinnate antiviral responses including the production of typeI IFN. Clone SS1A has been shown to be useful for western blotting of the mouse RIG-1protein.