PERYLENE-3,4,9,10-TETRACARBOXY

Use of Chiral Crown Ethers in Capillary Electrophoresis

Chiral crown ethers are known to include stereoselectively compounds containing primary amino groups. This principle has successfully been applied in liquid chromatography (LC) using crown ether-based stationary phases (1 –10 ). Kuhn et al

Peptide-Conjugated Quantum Dots: Imaging the Angiotensin Type 1 Receptor in Living Cells

Peptide-quantum dot conjugates have been prepared by attaching angiotensin II (Ang II) to cadmium selenide/zinc sulfide core-shell nanocrystals using an 1-[3-(Dimethyamino)propyl]-3-ethylcarbo diimide hydrochloride (EDC) coupling

mRNA 疫苗为何必须使用 LNP？四类核心脂质各自起什么作用？

perylene四环骨架，包含游离固醇、固醇酯、胆汁酸与类固醇激素。动物核心组分胆固醇可稳定细胞膜，亦是胆汁酸、类固醇激素、维生素 D 的合成前体；植物、微生物分别含谷甾醇、麦角固醇。这类脂质参与脂转运、内分泌调控等生理活动，也是 LNP 核酸递送体系的关键辅料。 图 5. 动物源胆固醇的结构式。   孕烯醇酮脂类 (prenol lipids) 孕烯醇酮脂类由五碳Isoprene单元缩合而成，是固醇合成关键前体，包含萜类、类胡萝卜素、辅酶 Q 10