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- 详细信息
- 技术资料
- 抗体英文名：
Anti-Mouse CD8a FITC
- 规格：
50ug
The 53-6.7 monoclonal antibody reacts with the mouse CD8a molecule.
CD8a is an approximately 32-34 kDa cell surface receptor expressed either as a
heterodimer with the CD8 beta chain (CD8 alpha beta) or as a homodimer (CD8 alpha alpha).
A majority of thymocytes and a subpopulation of mature alpha beta TCR T cells express CD8
alpha beta while gamma delta TCR T cells, a subpopulation of intestinal intraepithelial
lymphocytes (IELs) and dendritic cells express CD8 alpha alpha. CD8 binds to MHC class I
and through its association with protein tyrosine kinase p56lck plays a role in T cell
development and activation of mature T cells.
CD8a is an approximately 32-34 kDa cell surface receptor expressed either as a
heterodimer with the CD8 beta chain (CD8 alpha beta) or as a homodimer (CD8 alpha alpha).
A majority of thymocytes and a subpopulation of mature alpha beta TCR T cells express CD8
alpha beta while gamma delta TCR T cells, a subpopulation of intestinal intraepithelial
lymphocytes (IELs) and dendritic cells express CD8 alpha alpha. CD8 binds to MHC class I
and through its association with protein tyrosine kinase p56lck plays a role in T cell
development and activation of mature T cells.
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Anti-Mouse CD8a FITC
¥708
