EIF4EBP1 Antibody

EIF4EBP1 Antibody - Product infoApplication
WBPrimary AccessionQ13541Other AccessionNP_004086.1ReactivityHumanIsotypeIgG1,kClone Names319CT22.8.2Calculated MW12580 DaEIF4EBP1 Antibody - Additional infoGene ID1978Other Names
EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1Target/Specificity
This EIF4EBP1 monoclonal antibody is generated from mouse immunized with EIF4EBP1 recombinant protein.Dilution
WB~~1:100~250Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Precautions
EIF4EBP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.EIF4EBP1 Antibody - Protein InformationNameEIF4EBP1Function
Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.