- ¥1100
- ABGENT
- AP6413b
- 2026年01月12日
- WB
- H
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
STUB1 Antibody (C-term)
- 抗体英文名：
STUB1 Antibody (C-term)
- 应用范围：
WB
- 适应物种：
H
- 克隆性：
多克隆
- 规格：
100UL
STUB1 Antibody (C-term) - Product infoApplication
WB, IHCPrimary AccessionQ9UNE7Other AccessionQ9WUD1,Q5ZHY5,Q969U2ReactivityHumanPredictedMouse, ChickenIsotypeRabbit IgCalculated MW34856 DaSTUB1 Antibody (C-term) - Additional infoGene ID10273Other Names
STUB1; CHIP; E3 ubiquitin-protein ligase CHIP; Antigen NY-CO-7; CLL-associated antigen KW-8; Carboxy terminus of Hsp70-interacting protein; STIP1 homology and U box-containing protein 1Target/Specificity
This STUB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-231 amino acids from the C-terminal region of human STUB1.Dilution
WB~~1:1000
IHC~~1:50~100Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Precautions
STUB1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.STUB1 Antibody (C-term) - Protein InformationNameSTUB1SynonymsCHIPFunction
E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Collaborates with ATXN3 in the degradation of misfolded chaperone substrates: ATXN3 restricting the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. Ubiquitinates NOS1 in concert with Hsp70 and Hsp40. Modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. Mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation. Mediates polyubiquitination of DNA polymerase beta (POLB) at 'Lys-41', 'Lys-61' and 'Lys-81', thereby playing a role in base-excision repair: catalyzes polyubiquitination by amplifying the HUWE1/ARF- BP1-dependent monoubiquitination and leading to POLB-degradation by the proteasome. Mediates polyubiquitination of CYP3A4. Ubiquitinates EPHA2 and may regulate the receptor stability and activity through proteasomal degradation.Cellular Location
Cytoplasm.Tissue Location
Highly expressed in skeletal muscle, heart, pancreas, brain and placenta. Detected in kidney, liver and lung
WB, IHCPrimary AccessionQ9UNE7Other AccessionQ9WUD1,Q5ZHY5,Q969U2ReactivityHumanPredictedMouse, ChickenIsotypeRabbit IgCalculated MW34856 DaSTUB1 Antibody (C-term) - Additional infoGene ID10273Other Names
STUB1; CHIP; E3 ubiquitin-protein ligase CHIP; Antigen NY-CO-7; CLL-associated antigen KW-8; Carboxy terminus of Hsp70-interacting protein; STIP1 homology and U box-containing protein 1Target/Specificity
This STUB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-231 amino acids from the C-terminal region of human STUB1.Dilution
WB~~1:1000
IHC~~1:50~100Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Precautions
STUB1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.STUB1 Antibody (C-term) - Protein InformationNameSTUB1SynonymsCHIPFunction
E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Collaborates with ATXN3 in the degradation of misfolded chaperone substrates: ATXN3 restricting the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. Ubiquitinates NOS1 in concert with Hsp70 and Hsp40. Modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. Mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation. Mediates polyubiquitination of DNA polymerase beta (POLB) at 'Lys-41', 'Lys-61' and 'Lys-81', thereby playing a role in base-excision repair: catalyzes polyubiquitination by amplifying the HUWE1/ARF- BP1-dependent monoubiquitination and leading to POLB-degradation by the proteasome. Mediates polyubiquitination of CYP3A4. Ubiquitinates EPHA2 and may regulate the receptor stability and activity through proteasomal degradation.Cellular Location
Cytoplasm.Tissue Location
Highly expressed in skeletal muscle, heart, pancreas, brain and placenta. Detected in kidney, liver and lung
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文献和实验相关实验
于研究。 性能参数 LIST OF ANTBODY PRODUCTS AP8401a BDP1 N-term Antibody AP8408b MEG2 C-term Antibody AP8451b PPP3CA C-term Antibody AP8449b CTDSP1 C-term Antibody AP8408a MEG2 N-term Antibody AP8451a PPP3CA N-term Antibody AP8449
【资源】全面归类网址：毕赤酵母表达各种来源蛋白（细菌，真菌，植物，人类等）
europaea (olive tree) aeroallergen Ole e 1S, 60 mg/L, α-MF[115, 334, 391]Olea europaea 1,3-β-glucanase Ole e 9 C-term.seg.S, 100 mg/L, α-MF, active486Oleaceae sp. (lilac and privet) pollen allergensS, 30 mg/L, reactive481Pepper endo-b-1,4-glucanase cCel1S
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STUB1 Antibody (C-term)
¥1100
