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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
GCN5 Antibody (N-term)
- 抗体英文名：
GCN5 Antibody (N-term)
- 应用范围：
WB
- 适应物种：
H
- 克隆性：
多克隆
- 规格：
100UL
WBPrimary AccessionQ92830Other AccessionQ9JHD2,Q8N1A2ReactivityHumanPredictedMouseIsotypeRabbit IgCalculated MW93926 DaGCN5 Antibody (N-term) - Additional infoGene ID2648Other Names
KAT2A; GCN5; GCN5L2; HGCN5; Histone acetyltransferase KAT2A; General control of amino acid synthesis protein 5-like 2; Histone acetyltransferase GCN5; Lysine acetyltransferase 2A; STAF97Target/Specificity
This GCN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-94 amino acids from the N-terminal region of human GCN5.Dilution
WB~~1:1000Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Precautions
GCN5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.GCN5 Antibody (N-term) - Protein InformationNameKAT2ASynonymsGCN5, GCN5L2, HGCN5Function
Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.Cellular Location
Nucleus.Tissue Location
Expressed in all tissues tested, with most abundant expression in ovary
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文献和实验In the field of therapeutic recombinant proteins, monoclonal antibodies (mAbs) have achieved a rising success with more than 30 mAbs that have reached the market in the past 20 years. From a structural standpoint, one of the most important
to protect the antibody. These should be stored in smaller aliquots (about 1 ml) and frozen for long term storage though the protected solution is also stable for months at four degrees. Ascites fluid: This is a bit more problematic as it may contain
Materials 0.1M NaHC03 pH9 DMSO NHS-Biotin (N-Hydroxysuccinimidobiotin, Sigma #H-1759) PBS Procedure Dialyze the sample against carbonate buffer. After dialysis, adjust
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