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文献和实验3 篇 Nature 连发，解决世纪难题，周期蛋白的毁灭调控蕴含癌症患者的新生
for D-type cyclin proteins. DOI: https://doi.org/10.1038/d41586-021-00889-0.2. Daniele Simoneschi et al. Nature. CRL4AMBRA1 is a master regulator of D-type cyclins. DOI: https://doi.org/10.1038/s41586-021-03445-y.3. Andrea C. Chaikovsky et al. Nature
, other common mutations exist in most populations, each reaching frequencies of approx 1–2%. Examples include the 1717-1G→A, G542X, G551D, R553X, W1282X, and N1303K mutations. Finally, for a given ethnic population, “ethnic-specific” mutation(s) that reach
kinases activate the serine/threonine kinases M n k l and M n k 2 . EMBO J. 16, 1909-1920. 13. Fujita, H., Fujita, H., Takemura, M., et al. (2003) A n ArabidopsisM A D S - b o x protein, A G L 2 4 , is specifically bound to and phosphorylated
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