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文献和实验Activator-Dependent Acetylation of Chromatin Model Systems
1 promoter. Using this system as an example, here we describe the use of a combination of biochemical and biophysical methods to investigate the effect of activator-dependent acetylation on higher order chromatin structure and transcription by RNA polymerase
non-ATP competitive allosteric Akt inhibitor with IC50 of 8 nM,12 nM, 65 mM for Akt1, Akt2 and Akt3 respectively； The phase II clinical trials of MK-2206 against the treatment of endometrial cancer are recruiting participant Dana-Farber Cancer
相关专题 The PI3K/AKT and related pathways are important in internalizing the effects of external growth factors and of membrane tyrosine kinases. Activation of membrane kinases including epidermal growth factor receptor (EGFR) by external
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