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文献和实验Activation of Nuclear Factor-B (NF-B) in Mononuclear Cells (MNC)
in a rapid fashion (2 ). NF-κB interacts with its inhibitor protein IκB and activation of NF-κB causes it to move into the nucleus and this is controlled by the phosphorylation and subsequent degredation of IκB (3 ,4 ). The activated form of NF-κB
The nuclear factor-kappa B (NFκB) family of transcription factors has emerged as a signaling pathway that figures prominently in a cell’s initial response to a plethora of inflammatory stimuli. Modified lipids, oxidative stress, bacterial
Activation of Nuclear Factor-B
binding activity in the cultured human mast cell line HMC-1 using the electrophoretic mobility shift assay: the activation of NF-κB was illustrated by adding lipopolysaccharide to mast cells, nuclear proteins were isolated, and the NF-κB binding activity
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