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文献和实验Modulation of Potassium Ion Channel Proteins Utilising Antibodies
in neuronal function where specific agonists and antagonists do not exist, e.g. ion channel subunits. We discuss a way to utilise subunit specific antibodies to target individual channel subunits in electrophysiological experiments to determine functional
Photochromic Potassium Channel Blockers: Design and Electrophysiological Characterization
, increased excitability. We have developed a series of photosensitive blockers for K v channels that enable reversible, optical regulation of potassium ion flow. Such molecules can be used for remote control of neuronal excitability using light
BK Potassium Channel Mutations Affecting Neuronal Function and Epilepsy
. Recently, the large conductance voltage and calcium-activated potassium channel (BK channel) gene and their accessory subunits have been appended to the list of mutations causing epilepsy in humans and mice. BK channels have the specialized role
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