NFKB-BLA FS HEK293F CELLS

Nat Commun：结直肠癌致癌突变 RNF43_pG659fs 对 PI3K/mTOR 抑制剂敏感

RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition 的研究论文，揭示了 RNF43_p.G659fs 突变在结直肠癌的致癌机制，并对 PI3K/mTOR 抑制剂敏感。 RNF43 是一种 E3 泛素连接酶，Wnt 信号通路的主要负向调节因子，编码 783aa 的锌指蛋白，2014 年 Giannakis 团队在 Nature

Altered Expression of NFkB in Ex Vivo Differentiated Dendritic Cells from the Aged Subjects: Implications in Immunotherapy

Dendritic cells are the key initiators and organizers of the immune response. They are specialized antigen-presenting cells whose immunogenicity leads to the induction of antigen-specific immune responses. They are therefore ideal vehicles

Production of Bispecif ic and Trispecific F(ab)2 and F(ab)3 Antibody Derivatives

(drugs or toxins) or cellular effectors (T-cells, monocytes, or NK cells) to tumor cells (1 ,2 ). A relatively new development is the design of BsAbs to deliver chelated radiometals for the diagnostic imaging of tumors and for radioimmunotherapy (1 ).