- 询价
- Biotium
- 美国
- 50027
- 2025年09月10日
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- 详细信息
- 技术资料
- 英文名：
PROBENECID, SODIUM SALT *WATER SOLUBLE*, 77mg 50027
- 库存：
99
- 供应商：
Biotium
- CAS号：
23795-03-1
Probenecid is commonly used to inhibit organic-anion transporters located in the cell membrane. Such transporters can extrude dyes and indicators and thus contribute to low signal or high background in assays due to poor cellular retention of dyes. The use of probenecid to block the efflux of intracellular dyes was first described by Di Virgilio et al. (1990), and it has been used with a wide range of anionic dyes and conjugates. The commonly used free acid form of probenecid is difficult to dissolve, requiring 1M NaOH to prepare a solution. Our water-soluble probenecid sodium salt dissolves quickly in assay buffer and eliminates the need for handling caustic NaOH. Each vial is directly dissolved in 1 mL buffer to make a 250 mM stock solution. Typical working concentrations in cell-based assays are 1-2.5 mM.
- Colorless solid soluble in water (77 mg/mL of water)
- C13H18NNaO4S
- MWt: 307.34
- Store desiccated at room temperature
- [23795-03-1]
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