RHODAMINE 110, BIS-(L-ASPARTIC

D2R是caspases包括caspase3和7的底物。和其他caspases荧光底物不同的是，D2R是膜透性的，因此可用于活细胞caspase活性检测，而不必进行流式细胞仪研究的渗透震扰。

D₂R (Rhodamine 110, bis-(L-aspartic acid amide), ditrifluoroacetic acid salt) is a general substrate for caspases including caspases 3 and 7. Unlike other fluorogenic substrates for caspases, D₂R appears to be membrane-permeant, and thus can be used to measure caspase activity in live cells without osmotic shock for flow cytometry studies, as well as for cell extracts. For real-time detection of caspase-3 activity in intact cells, see our novel NucView®488 Caspase-3 Substrate.

• Ex/Em of end product (R110) = 496/520 nm
• Off-white to pink solid soluble in DMSO
• Store at 4°C and protect from light
• C₃₂H₂₆F₆N₄O₁₃
• MW: 788.57