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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
for future use below -18°C
- 保质期:
See instructions
- 英文名:
IL10
- 库存:
部分小规格有备货
- 供应商:
上海经科化学科技有限公司
- CAS号:
无
- 规格:
2ug/10ug/1mg
| 规格: | 2ug | 产品价格: | ¥1080.0 |
|---|---|---|---|
| 规格: | 10ug | 产品价格: | ¥2415.0 |
| 规格: | 1mg | 产品价格: | ¥79695.0 |

CATALOGUE NUMBER
CYT-500
SYNONYMS
INTRODUCTION
Recombinant IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
DESCRIPTION
The IL-10 is purified by proprietary chromatographic techniques.
SOURCE
PHYSICAL APPEARANCE
FORMULATION
SOLUBILITY
STABILITY
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
PURITY
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
AMINO ACID SEQUENCE
BIOLOGICAL ACTIVITY
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文献和实验1.Title:Activated signal transducer and activator of transcription-3 (STAT3) is a poor regulator of tumour necrosis factor- production by human monocytes.
Publication:Article first published online: 9 JAN 2007 DOI:10.1111/j.1365-2249.2006.03291.x
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