人胃饥饿素GhrelinELISA试剂盒

人胃饥饿素GhrelinELISA试剂盒

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  • ¥7600
  • cayman
  • USA
  • 10008952-96
  • 2025年09月30日
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    • 详细信息
    • 询价记录
    • 技术资料
    • 库存

      3-4周

    • 供应商

      上海研卉生物

    • 检测方法

      酶免

    • 应用

      elisa 体外检测

    • 规格

      96T

    胃饥饿素(人,未乙酰化)检测ELISA试剂盒
    Ghrelin (human unacylated) EIA Kit
    原装进口,拒绝假货。
    本公司提供饥饿素(GHRL)检测试剂盒(酶联免疫吸附试验法)
    ELISA Kit for Ghrelin (GHRL) 进口产品国内生产,价格3500元/96T
    参考文献 Expression of ghrelin in human salivary glands and its levels in saliva and serum in Chinese obese children and adolescents
    引用杂志 Archives of Oral Biology 阅读[PubMed: 21075359]
    参考文献 The modifying effects of fish oil on fasting ghrelin mRNA expression in weaned rats
    引用杂志 Gene 阅读[PubMed: 22842192]

    胃饥饿素(生长素)是生长激素促分泌受体的内源配体,在胃中合成的。它可以促进食物的摄取并转换信号至下丘脑,调整体内的能量平衡。这个肽段还有28个氨基酸,3号丝氨酸发生辛酰化,这是生物活性所必需的。存在于外周循环系统的胃饥饿素有两种形式,即乙酰化和非乙酰化。
    Cayman的胃饥饿素(人,未乙酰化)检测Elisa试剂盒特异性的检测未乙酰化的胃饥饿素。试剂盒中含有未乙酰化的胃饥饿素-Fab片段,大鼠未乙酰化的胃饥饿素标准液,预包被抗胃饥饿素抗体的板子以及相关的检测试剂
    Cayman的胃饥饿素(人,未乙酰化)检测Elisa试剂盒,检测的极限:免疫孵育20小时后的检测极限值是6pg/ml,孵育3小时后的检测极限值是8pg/ml·存储温度为-20度,稳定期6个月。

    Ghrelin (human unacylated) EIA Kit

    Cayman Chemical Item Number 10008952

    Ghrelin (human unacylated) ELISA Kit

    人胃饥饿素GhrelinELISA试剂盒
    See more
    Limit of detection: 2 pg/ml after 20 hour immunological incubation; 6 pg/ml after 3 hour immunological incubation · Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor, is synthesized principally in the stomach. It stimulates food intake and transduces signals to hypothalamic regulatory nucleid that controls energy homeostasis. The peptide consists of 28 amino acids, with a n-octanoylation of the serine-3 residue, which is necessary for biological activity. Ghrelin is present in the peripheral circulation in two forms: acylated and unacylated. This EIA kit specifically measures the unacylated form of ghrelin. Each kit contains ghrelin (unacylated) AChE-Fab' conjugate, human unacylated ghrelin standard, human unacylated ghrelin quality control, Ellman’s reagent, EIA buffer, wash buffer, Tween 20, plates pre-coated with anti-ghrelin mouse monoclonal antibody, and complete instructions.
    Synonyms
    • Ghrelin (human unacylated) ELISA Kit
    Formal Name
    Stability 6 months
    Storage -20°C
    Shipping Wet ice in continental US; may vary elsewhere
    Specificity
    Rat Ghrelin Des-Octanoyl-Ser3 100%
    Human Ghrelin Octanoyl-Ser3 <0.06%
    Mouse Ghrelin Octanoyl-Ser3 <0.03%
    Show all 17

    Ghrelin Human ELISA Kit thermo公司

    货号:BMS2192 价格4600元/96T.

    描述

    Ghrelin was originally isolated from the stomach, but ghrelin has also been identified in other peripheral tissues, such as the gastrointestinal tract, pancreas, ovary and adrenal cortex. It regulates both appetite and rate of use of energy. When the stomach is empty, ghrelin is secreted. When the stomach is stretched, secretion stops. It acts on hypothalamic brain cells both to increase hunger, and to increase gastric acid secretion and gastrointestinal motility to prepare the body for food intake. In addition, ghrelin levels show a diurnal variation and seem to be influenced by age, gender, BMI, growth hormone (GH), glucose and insulin.

    The gene coding for human prepro-ghrelin, GHRL, is located on chromosome 3 (3p25-26) and is composed of four exons and three introns spanning 5 kb. Human prepro-ghrelin consists of 117 amino acids, and the mature ghrelin peptide is constituted of 28 amino acids with a fatty acid chain modification (octanoyl group) on the third amino acid.

    As a growing number of people suffer from obesity, understanding the mechanisms by which various hormones and neurotransmitters have influence on energy balance has been a subject of intensive research. Ghrelin, unlike the case of many other endogenous peptides, is able to cross the blood-brain-barrier, giving exogenously-administered ghrelin unique clinical potential.

    Suitable Sample Types
    Serum, plasma (citrate, heparin, EDTA) and cell culture supernatant

    Sample Volume
    25 µL

    Reported Application
    ELISA
    Assay Range: 15.6-1,000.0 pg/mL
    Assay Sensitivity: 11.8 pg/mL
    Detection Method: Colorimetric
    Detector Antibody Conjugate: Biotin

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