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- 详细信息
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Phospho-Tau Protein (Thr489).
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
H, M, R
- 保质期:
1-2年
- 抗原来源:
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Phospho-Tau Protein (Thr489).
- 目录编号:
251362
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Rabbit
- 应用范围:
E, WB, IHC
- 浓度:
见详细说明信息
- 靶点:
Phospho-Tau Protein (Thr489)
- 抗体英文名:
Phospho-Tau Protein (Thr489) Antibody
- 抗体名:
Phospho-Tau Protein (Thr489) Antibody
- 规格:
0.1 mg
Phospho-Tau Protein (Thr489) Antibody产品详细介绍:
| 产品名称: | Phospho-Tau Protein (Thr489) Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 251362 |
| 规格: | 0.1 mg |
| 产品描述: | Microtubule-associated protein tau (tau protein) promotes microtubule assembly and stability, and is involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms preferentially play a role in its stabilization. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease and other tauopathies. |
| 克隆类型: | Rabbit Polyclonal Antibody, Phosphospecific Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Phospho-Tau Protein (Thr489). |
| 适用物种: | H, M, R |
| 应用范围: | E, WB, IHC |
| 应用说明: | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别名: | Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; MAPT PHF-tau; MAPTL; MTBT1, TAU; Phospho-Tau Protein (Thr489) |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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Phospho-Tau Protein (Thr489) Antibody_Phospho-Tau Protein (Thr489)抗体
¥3000 - 3999










