- ￥3000 - 3999
- Abbiotec
- 美国
- 253104
- 2025年11月21日
- WB
- Mouse
- H
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Purified recombinant fragment of human ATXN1 expressed in E. coli.
- 亚型：
Mouse IgG1
- 形态：
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
- 保存条件：
Store at -20°C
- 克隆性：
单克隆
- 标记物：
见下方详细说明
- 适应物种：
H
- 保质期：
1-2年
- 抗原来源：
Purified recombinant fragment of human ATXN1 expressed in E. coli.
- 目录编号：
253104
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Mouse
- 应用范围：
WB
- 浓度：
见详细说明信息
- 靶点：
ATXN1 (2F5)
- 抗体英文名：
ATXN1 (2F5) Antibody
- 抗体名：
ATXN1 (2F5) Antibody
- 规格：
0.1 ml
ATXN1 (2F5) Antibody产品详细介绍：
| 产品名称： | ATXN1 (2F5) Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 253104 |
| 规格： | 0.1 ml |
| 产品描述： | Ataxin-1 is a chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Ataxin-1 is related to autosomal dominant cerebellar ataxias (ADCA). ADCA is a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. Ataxin-1 is widely expressed throughout the body. |
| 克隆类型： | Mouse Monoclonal Antibody |
| 亚型： | Mouse IgG1 |
| 免疫原： | Purified recombinant fragment of human ATXN1 expressed in E. coli. |
| 适用物种： | H |
| 应用范围： | WB |
| 应用说明： | WB: 1:500-1:2000; |
| 别名： | Ataxin-1; Spinocerebellar ataxia type 1 protein; ATX1; SCA1; ATXN1 |
| 形态： | Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存条件： | Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 参考文献： |
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