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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
This ATXN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 754-781 amino acids from human ATXN1.
- 保存条件:
Store at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
WB, IF
- 抗体英文名:
ATXN1 Antibody
- 抗体名:
ATXN1 Antibody
- 规格:
400ul
ATXN1 抗体 ,ATXN1 Antibody ,ATXN1 抗体 ,ATXN1 Antibody
产品名称:ATXN1 抗体 -ATXN1 Antibody
产品货号:PSI-61-519-400ul
产品规格:400ul
背景资料:The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known.
保存建议:ATXN1 抗体 -ATXN1 Antibody Store at 4℃ for three months and -20℃, stable for up to one year
应用类型:WB, IF
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