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- MERCK
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- US1444937-5MG
- 2025年07月15日
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- 详细信息
- 文献和实验
- 技术资料
- 保质期：
1年
- 英文名：
MEK INHIBITOR I
- 供应商：
北京智杰方远科技
- CAS号：
******
- 保存条件：
详见说明
- 规格：
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文献和实验Detecting Mechanisms of Acquired BRAF Inhibitor Resistance in Melanoma
or alternative splicing, and MEK mutation have been reported as acquired BRAFi resistance mechanisms. Clinially, detection of these resistance mechanisms help understand drug response patterns and help guide combinatorial therapeutic strategies. Therefore, quick
Generation of Novel Rat and Human Pluripotent Stem Cells by Reprogramming and Chemical Approaches
) have been generated from both mouse and human somatic cells by genetic transduction. We had successfully established novel rat iPSCs (riPSCs), which can be homogenously maintained by LIF and a cocktail of ALK5 inhibitor, GSK3 inhibitor and MEK inhibitor. riPSCs share
is a highly selective inhibitor of MEK1 and MEK2 with IC50 values of 4 ?M and 50 ?M respectively. PD98059 does not inhibit activation of other highly related dual-specificity protein kinases or the activity of over 18 other Ser/Thr protein kinases
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