PF-4708671

1) Cat. No.: TRC-P294010; 2) Chemical Name: PF-4708671 ; 3) CAS No.: 1255517-76-0; 4) Mol. Formula: C19H21F3N6; 5) Mol. Weight: 390.41; 6) Packing Size: 10mg / 100mg; 7) Appearence: Pale purple Solid; 8) Application Notes: PF-4708671 is a highly specific inhibitor of p70 ribosomal S6 kinase (S6K1). PF-4708671 inhibits S6K1-mediated phosphorylation of S6 protein in response to IGF-1 (insulin-like growth factor 1), while having no effect on highly related RSK (p90 ribosomal S6 kinase) and MSK (mitogen- and stress-activated kinase) kinases.; 9) Synonym: 2-[[4-(5-ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-1H-benzimidazole; PF 4708671; ; 10) Solubility: DMSO, Methanol; 11) Storage condition: -20˚C Freezer; 12) References: Pearce, L.R. et al.: Biochem. J., 431, 245 (2010);