Mirodenafil Dihydrochloride

1) Cat. No.: TRC-M364950; 2) Chemical Name: Mirodenafil Dihydrochloride; 3) CAS No.: 862189-96-6; 4) Mol. Formula: C26H39Cl2N5O5S; 5) Mol. Weight: 604.59; 6) Packing Size: 25mg / 50mg; 7) Appearence: ; 8) Application Notes: Mirodenafil, a phosphodiesterase 5 inhibitor reported to be effective in the treatment of erectile dysfunction, is metabolized by cytochrome P 450 (CYP) 3A4 to the active metabolite N-dehydroxyethyl mirodenafil. Mirodenafil may have drug-drug interactions with ketoconazole and/or rifampicin. ; 9) Synonym: 5-Ethyl-3,5-dihydro-2-[5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]-2-propoxyphenyl]-7-propyl-4H-pyrrolo[3,2-d]pyrimidin-4-one Hydrochloride; 4-[[3-(5-Ethyl-4,5-dihydro-4-oxo-7-propyl-1H-pyrrolo[3,2-d]pyrimidin-2-yl)-4-propoxyphenyl]sulfonyl]-1-piperazineethanol Dihydrochloride; SK 3530; ; 10) Solubility: ; 11) Storage condition: ; 12) References: Matheny, C., et al.: Drug Metab. Dispos., 32, 1008 (2004), Gupta, M., et al.: J. Clin. Pharmacol., 45, 987 (2005), Ek, M., et al.: Biochem. Pharmacol., 74, 496 (2007), Lee, H., et al.: Xenobiotica, 38, 21 (2008),