L-798106

1) Cat. No.: TRC-L011500; 2) Chemical Name: L-798106 ; 3) CAS No.: 244101-02-8; 4) Mol. Formula: C27H22BrNO4S; 5) Mol. Weight: 536.44; 6) Packing Size: 10mg / 100mg; 7) Appearence: ; 8) Application Notes: L-798106 is a potent and selective prostanoid receptor EP3-selective antagonists. L-798106 has been used in multiple studies to tease out EP3 agonist activity, both in vitro and in vivo. L-798106 successfully blocks the actions of sulprostone, an EP3-selective agonist. L-798106 was useful in showing that the vascular contraction effect of PGE2 is due to its prostanoid EP3 agonist activity.; 9) Synonym: (2E)-N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide; CM 9; GW 671021; ; 10) Solubility: ; 11) Storage condition: ; 12) References: Kobayashi, K. et al.: Eur. J. Pharmacol., 660, 375 (2011); Su, X. et al.: Am. J. Physiol. Renal Physiol., 295, F984 (2008); Bassil, A.K. et al.: Br. J. Pharmacol. 154, 126 (2008); Jugus, M.J. et al.: Br. J. Pharmacol., 158, 372 (2009); Juteau, H. et al.: Bioorg. Med. Chem., 9, 1977 (2001);