HX 630

1) Cat. No.: TRC-H674250; 2) Chemical Name: HX 630; 3) CAS No.: 188844-52-2; 4) Mol. Formula: C28H27NO2S; 5) Mol. Weight: 441.58; 6) Packing Size: 100mg / ; 7) Appearence: ; 8) Application Notes: A nuclear receptor retinoid X receptor (RXR) agonist that exerts antiproliferative effects in vascular smooth muscle cells (VSMCs) in vivo and in vitro. A potential therapeutic target for vascular injury and intimal thickening. It efficiently enhanced ABCA1 mRNA expression and apoA-I-dependent cellular cholesterol release in differentiated THP-1 cells.; 9) Synonym: 4-(7,8,9,10-tetrahydro-7,7,10,10-tetramethylbenzo[b]naphtho[2,3-f][1,4]thiazepin-12-yl)benzoic Acid;; 10) Solubility: ; 11) Storage condition: ; 12) References: Haraguchi, G. et al.: J. Mol. Cell. Cardiol., 41, 885 (2006); Nishimaki-M. et al.: Biochem. Pharmacol., 76, 1006 (2008);