6-Cyano-7-nitroquinoxaline-2,3

1) Cat. No.: TRC-C982000; 2) Chemical Name: 6-Cyano-7-nitroquinoxaline-2,3-dione; 3) CAS No.: 115066-14-3; 4) Mol. Formula: C9H4N4O4; 5) Mol. Weight: 232.15; 6) Packing Size: 10mg / 100mg; 7) Appearence: Pale Yellow Solid; 8) Application Notes: A potent, competitive kainate/quisqualate (non-NMDA) receptor antagonist. IC50 of tritiated ligands to rat cortical membranes by CNQX: AMPA, Kainate and CPP are 0.3mM, 1.5mM, and 25mM, respectively.; 9) Synonym: 1,2,3,4-Tetrahydro-7-nitro-2,3-dioxo-6-quinoxalinecarbonitrile; CNQX; 6-Cyano-2,3-dihydroxy-7-nitroquinoxaline; ; 10) Solubility: Dilute Aqueous Base, DMSO; 11) Storage condition: Refrigerator; 12) References: Honore, et al. Science, 241, 701 (1988),Haas, H.S., et al.: Int. J. Oncol., 27, 867 (2005), Kobayashi, K., et al.: J. Pharmacol. Sci., 108, 517 (2008), Shabat-Simon, M., et al.: J. Neurosci., 28, 8406 (2008), Cruz, L.A., et al.: J. Med. Chem., 51, 5856 (2008),