9-Amino-1,2,3,4-tetrahydroacri

1) Cat. No.: TRC-A629700; 2) Chemical Name: 9-Amino-1,2,3,4-tetrahydroacridine Hydrochloride Dihydrate; 3) CAS No.: 1684-40-8; 4) Mol. Formula: C13H19ClN2O2; 5) Mol. Weight: 270.76; 6) Packing Size: 2.5g / 25g; 7) Appearence: Pale Yellow Solid; 8) Application Notes: A potent centrally acting anticholinesterase, for therapy of memory deficits in patients with Alzheimers's disease. THA also selectively blocks potassium channels in the central nervous system, which results in an increased release of acetylcholine and a prolongation of the action potential of the presynaptic cholinergic neurons.; 9) Synonym: 1,2,3,4-Tetrahydro-9-Acridinamine Hydrochloride Dihydrate; Hydroaminacrine Dihydrate; Romotal Dihydrate; THA Dihydrate; Tacrine Hydrochloride Dihydrate; Tenakrin Dihydrate;; 10) Solubility: DMSO, Methanol; 11) Storage condition: -20°C Freezer; 12) References: Harper, J., et al.: Chem. Biol., 4, 119 ( 1997), Kirkitadze, M., et al.: J. Mol. Biol., 312, 1103 (2001), Zhuang, Z., et al.: J. Med. Chem., 44, 1905 (2001), Necula, M.J., et al.: Biol. Chem., 282, 10311 (2007),