Aflatoxin B1-d3

1) Cat. No.: TRC-A357462; 2) Chemical Name: Aflatoxin B1-d3; 3) CAS No.: ; 4) Mol. Formula: C17H9D3O6; 5) Mol. Weight: 315.29; 6) Packing Size: 0.25mg / 1mg; 7) Appearence: Pale Yellow Solid; 8) Application Notes: Aflatoxin B1 labelled standard. Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Aflatoxin is biotransformed to genotoxic intermediates by P450 Phase I enzymes, mainly CYP3A4 via aflatoxin B1 3-hydroxylation. Detoxification depends on Phase II enzymes, such as Glutathione S-Transferase and AFB(1)-aldehyde reductase (AFAR). Aflatoxin B1 is one of the most potent environmental mutagens and carcinogens known. ; 9) Synonym: (6aR,9aS)-2,3,6a,9a-Tetrahydro-4-(methoxy-d3)-1H,11H-cyclopenta[c]furo[3’,2’:4,5]furo[2,3-h][1]benzopyran-1,11-dione; (-)-Aflatoxin B1-d3; AFB1-d3; NSC 529592-d3;; 10) Solubility: Chloroform; 11) Storage condition: -20˚C Freezer; 12) References: Cifford, R., et al.: Nature, 209, 312 (1966), Wogan, et al.: Food Cosmet. Toxicol., 12, 681 (1974), Sinz, M.W., et al.: J. Toxicol. Toxin Rev., 10, 87 (1991),