Etanercept Biosimilar - Resear

Etanercept Biosimilar - Research Grade. Clonality: Recombinant. Host: Humanized. Reactivity: Human. Form: Liquid. Purity: >95% by SDS-PAGE and HPLC. Storage: Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.. This is an unconjugated, non-therapeutic recombinant analog of etanercept supplied strictly for research use. Etanercept is a soluble decoy built by fusing the extracellular ligand-binding portion of the p75 TNF receptor (TNFR2/TNFRSF1B) to the Fc region of human IgG1; it works by capturing soluble TNF alpha (and lymphotoxin-alpha) before they can engage cell-surface TNF receptors. The research-grade analog reproduces this TNF-binding decoy activity, making it a useful tool for interrogating TNF