LD Biopharma Recombinant Human

Recombinant Human ACPP-11R Protein，品牌LD Biopharma，货号HRP-0128，规格50 µg / Vial。 基因符号：ACPP 登录号：NP_001090.2 (Isoform 1) 物种：Human 质量控制：1. Purity: > 90% by SDS-PAGE. 2. Other functional activities: Not tested yet. 制剂组成：0.5 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol. 英文说明：PHuman ACPP (acid phosphatase, prostate) gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. This protein was used as human prostate cancer vaccines (Provenge), which FDA accepted in 2010 for treatment of advanced prostate cancer that has metastasis. Recombinant human ACPP-11R protein was constructed with C-terminal tag of 11 arginine domain, which will efficiently deliver protein intracellularly. This protein was expressed in E. coli, refolded using our unique “temperature shift inclusion body refolding” technology and chromatographically purified. Incubating this protein in various culture media at 2 – 8 µg/ml may be used for studying of human prostate cancer treatment using intracellular protein delivery strategy for immuno-stimulation. 应用信息：1. Human prostate specific tumor antigen. 2. Immunogen for specific antibody production. 本品仅供科研使用。实际构建、质量控制、保存及使用要求请以批次文件为准；网站目录不代表当前库存或实际供货承诺。