【干冰】DNA Polymerase γ (POLG), H

Purification Strategies for Drosophila mtDNA Replication Proteins in Native and Recombinant Form: DNA Polymerase

assay that differentiates the mitochondrial form from what generally prove to be multiple, and much more abundant, nuclear counterparts. A case in point is the mitochondrial DNA polymerase, pol γ. Pol γ was the third DNA polymerase identified in animal

Functional Analysis of Mutant Mitochondrial DNA Polymerase Proteins Involved in Human Disease

DNA polymerase γ (pol γ) is the only DNA polymerase within the mitochondrion and is thus essential for replication and repair of mtDNA. POLG , the gene encoding the catalytic subunit of pol γ, is a major locus for a wide spectrum

Comparative Purification Strategies for Drosophila and Human Mitochondrial DNA Replication Proteins: DNA Polymerase and Mitochondrial Single-Stranded

involving nuclear-encoded proteins that are required at the mitochondrial DNA replication fork, which often leads to human disorders and to animal lethality during development. DNA polymerase γ (pol γ), the mitochondrial replicase, and the mitochondrial