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- 文献和实验
- 技术资料
- 库存:
42
- 供应商:
广州市左克生物
- 规格:
100 μg
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产品简介:
货号:Z05646-100
产品名称:MFAP5 hFc Chimera, Human
产品规格:100 μg
产品介绍文本:Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-associated protein 5 (MFAP5) plays an important role in the integration of elastic...
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产品属性HTML:
产品简介HTML:
| Species | Human | ||||
| Protein Construction |
|
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| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 44.1 kDa | ||||
| Apparent Molecular Weight | Due to furin cleavage and glycosylation, the protein migrates to 32-38 kDa and 55-65 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
应用指导HTML:
技术背景HTML:
| Target Background | Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-associated protein 5 (MFAP5) plays an important role in the integration of elastic microfibers and the regulation of endothelial cell behaviors.MFAP5 was significantly overexpressed in BLBC tissues and associated with poor metastasis-free survival of patients with BLBC. |
| Synonyms | MFAP-5; MAGP-2; MAGP2; MP25; AAT9 |
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