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- 2026年08月13日
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- 文献和实验
- 技术资料
- 库存：
999
- 英文名：
PTRH2
- 保质期：
Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.
- 供应商：
北京索莱宝科技有限公司
- 保存条件：
Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.
- 规格：
10ug/50ug/100ug/1mg
| 规格： | 10ug | 产品价格： | ¥560.00 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ¥1120.00 |
| 规格： | 100ug | 产品价格： | ¥1800.00 |
| 规格： | 1mg | 产品价格： | ¥11200.00 |
| 基因名 | PTRH2 |
| 别名 | BIT1;PTH2;CGI-147 |
| 蛋白号 | Q9Y3E5 |
| 种属 | Human |
| 宿主 | E.coli |
| 产品描述 | Recombinant Human PTRH2 protein (Antigen) is produced by our E.coli expression system and the target gene encoding 41-179aa is expressed with a N-6His tag. |
| 区间范围 | 41-179aa |
| 标签信息 | N-6His |
| 预测分子量 | 15.18 kDa |
| 表观分子量 | 15 kDa |
| 纯度 | ≥85% by SDS-PAGE. |
| 内毒素 | Not measured |
| 溶剂 | Lyophilized from a 0.45μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, PH7.2-8.0. |
| 复溶 | Reconstituted protein solution can be diluted with distilled water. Always centrifuge tubes before opening. It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| 储存条件 | Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: 2-8°C for 2-7 days under sterile conditions after redissolves; -20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; -20°C to -70℃ for 12 months in lyophilized state. |
| 运输条件 | 冷冻运输 |
| 背景说明 | The protein encoded by this gene is a mitochondrial protein with two putative domains, an N-terminal mitochondrial localization sequence, and a UPF0099 domain. In vitro assays suggest that this protein possesses peptidyl-tRNA hydrolase activity, to release the peptidyl moiety from tRNA, thereby preventing the accumulation of dissociated peptidyl-tRNA that could reduce the efficiency of translation. This protein also plays a role regulating cell survival and death. It promotes survival as part of an integrin-signaling pathway for cells attached to the extracellular matrix (ECM), but also promotes apoptosis in cells that have lost their attachment to the ECM, a process called anoikos. After loss of cell attachment to the ECM, this protein is phosphorylated, is released from the mitochondria into the cytosol, and promotes caspase-independent apoptosis through interactions with transcriptional regulators. This gene has been implicated in the development and progression of tumors, and mutations in this gene have been associated with an infantile multisystem neurologic, endocrine, and pancreatic disease (INMEPD) characterized by intellectual disability, postnatal microcephaly, progressive cerebellar atrophy, hearing impairment, polyneuropathy, failure to thrive, and organ fibrosis with exocrine pancreas insufficiency (PMID: 25574476). Alternative splicing results in multiple transcript variants encoding different isoforms. |
| 细胞活性 | Non-active. |
| ELISA活性 | No activity experimental data, to be verified. |
| SPR/BLI活性 | No activity experimental data, to be verified. |
| 研究领域 | 生物制药相关研究 |
| 英文名称 | PTRH2 |
| 中文名称 | PTRH2蛋白 |
| 单位 | 支 |
| 规格 | 1mg ; 100ug ; 50ug ; 10ug |
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