重组人金属蛋白酶抑制剂2(TIMP2)

产品英文名称：
Recombinant Human Tissue Inhibitor of Metalloprotease 2

英文简称:
TIMP2

中文名称:
重组人金属蛋白酶抑制剂2

背景资料:
TIMP2 belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases， a group of peptidases that take part in degradation of the extracellular matrix. Besides having an inhibitory role against metalloproteinases， the encoded protein has a exclusive part among TIMP family members in its capability to directly suppress the proliferation of endothelial cells. Consequently， the encoded protein is crucial to the conservation of tissue homeostasis by suppressing the production of quiescent tissues as an answer to angiogenic factors， and by inhibiting protease activity in tissues undergoing renovation of the extracellular matrix.

产品描述:
TIMP2 Human Recombinant produced in E. coli is a single polypeptide chain containing 232 amino acids（27-220) and having a molecular mass of 26.1 kDa. TIMP2 is fused to a 38 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
来源宿主:
大肠杆菌中重组表达

溶解建议:
提供的重组人金属蛋白酶抑制剂2产品形式为无菌的无色溶液.

保存建议：
人金属蛋白酶抑制剂2蛋白产品可整瓶4℃保存2-4周，长期保存请置于-20℃.推荐添加载体蛋白（0.1% HSA或BSA)以长期保存，请避免反复冻融.
应用领域：
重组人金属蛋白酶抑制剂2产品可广泛应用于酶活性研究、代谢研究、功能研究、蛋白互作研究、ELISA检测、Western Blot、免疫组化等生物医学研究领域。

关键词：
重组人金属蛋白酶抑制剂2、Recombinant Human Tissue Inhibitor of Metalloprotease 2、TIMP2、重组蛋白、多肽、酶类、原核表达、标签蛋白

其他简介：

 
CMBIO