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- 文献和实验
- 技术资料
- 抗体名:
Histone H2B (Acetyl-K15) Rabbit Polyclonal Antibody 抗体
- 抗体英文名:
Histone H2B (Acetyl-K15) Rabbit Polyclonal Antibody
- 靶点:
HIST1H2BC
- 应用范围:
IHC, WB
- 宿主:
Rabbit
- 适应物种:
Human, Mouse, Rat
- 保质期:
12 months from date of receipt.
- 抗原来源:
详询
- 目录编号:
orb334675
- 级别:
科研
- 库存:
99
- 供应商:
Biorbyt
- 标记物:
Unconjugated
- 克隆性:
Polyclonal
- 保存条件:
详询
- 形态:
Liquid
- 免疫原:
详询
- 规格:
30 ul/50 ul/100 ul/200 ul
| 规格: | 30 ul | 产品价格: | ¥1872.0 |
|---|---|---|---|
| 规格: | 50 ul | 产品价格: | ¥2340.0 |
| 规格: | 100 ul | 产品价格: | ¥3627.0 |
| 规格: | 200 ul | 产品价格: | ¥5148.0 |
产品子类型: Primary Antibody
描述: The Histone H2B (Acetyl-K15) Antibody is suitable for IHC, WB. It is a Polyclonal, Unconjugated antibody which raised against KLH-conjugated synthetic acetylated peptide corresponding to residues surrounding K15 of human Histone H2B protein. The exact sequence is proprietary. Purification: The antibody was purified by immunogen affinity chromatography.
别名: HIST1H2BA; TSH2B; Histone H2B type 1-A; Histone H2B testis; Testis-specific histone H2B; HIST1H2BB; H2BFF; Histone H2B type 1-B; Histone H2B.1; Histone H2B.f; H2B/f; HIST1H2BC; H2BFL; HIST1H2BE; H2BFH; HIST1H2BF; H2BFG; HIST1H2BG; H2BFA; HIST1H2BI; H2BFK; Histone H2B type 1-C/E/F/G/I; Histone H2B.1 A; Histone H2B.a; H2B/a; Histone H2B.g; H2B/g; Histone H2B.h; H2B/h; Histone H2B.k; H2B/k; Histone H2B.l; H2B/l
应用稀释比例: WB: 1:200-1:500, IHC-P: 1:200-1:500
免疫原: KLH-conjugated synthetic acetylated peptide corresponding to residues surrounding K15 of human Histone H2B protein. The exact sequence is proprietary.
防腐剂: 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
纯化方法: The antibody was purified by immunogen affinity chromatography.
特异性: Recognizes endogenous levels of Histone H2B protein only when acetylated at K15.
研究领域: Epigenetics & Chromatin
UniProt ID: Q96A08, Q64475, P70696, Q6ZWY9, Q00729, P62807, P33778
Entrez 基因 ID: 8347, 255626, 319177, 8344, 3018, 319178, 319179, 8346, 8339, 8343, 24829, 3017
保存条件: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
备注: For research use only.


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文献和实验," made up of fragments of up to seven nucleosomes in length, is incubated with an antiserum directed against the histone modification of interest. The antibody-bound fraction is separated from the unbound fraction and, after extraction of genomic DNA from the bound
祝贺〖雅裕睿安〗成为Signalway Antibody(SAB)独家
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的转录,影响着基因的表达。组蛋白的乙酰化和去乙酰化能打开或关闭某些基因,增强或抑制某些基因的表达。例如H2B蛋白能在Lysines5,12,15和20乙酰化,H3蛋白能在Lysines9,14,18和23乙酰化。Lysines9的乙酰化在组蛋白的堆积和染色质的装配中起了关键的作用。而这种作用最终影响了基因的表达。在多种疾病中,都存在组蛋白编码错误的迹象。因此,有人将组蛋白编码称之为“第二套遗传密码”。组蛋白的乙酰化修饰对于研究基因的表达调控至关重要。目前尚缺乏能准确识别乙酰化和非乙酰化蛋白的抗体
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