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UBC9/UBE2I, Human, 重组蛋白

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  • ¥234 - 2197
  • TargetMol
  • TMPY-02608
  • 2026年07月07日
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      5μg/10μg/20μg/50μg/100μg

    规格:5μg产品价格:¥234.0
    规格:10μg产品价格:¥346.0
    规格:20μg产品价格:¥574.0
    规格:50μg产品价格:¥1103.0
    规格:100μg产品价格:¥2197.0

    Product Introduction

    Bioactivity

    名称 UBC9/UBE2I Protein, Human, Recombinant
    描述 UBE2I is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction. Initially identified as the main process for protein degradation, ubiquitination is believed nowadays to be crucial for a wider range of cellular processes. The outcome of the ubiquitin-conjugation reaction, and thereby the fate of the substrate, is heavily dependent on the number of ubiquitin molecules attached and how these ubiquitin molecules are inter-connected. To deal with this complexity and to allow adequate ubiquitination in time and space, a highly sophisticated conjugation machinery has been developed. In a sequential manner, ubiquitin becomes activated by a ubiquitin-activating enzyme (E1), which then transfers the ubiquitin to a group of ubiquitin-conjugating enzymes (E2s). Next, ubiquitin-loaded E2s are interacting with ubiquitin-protein ligases (E3s) and ubiquitin is conjugated to substrates on recruitment by the E3. These three key enzymes are operating in a hierarchical system, wherein two E1s and 35 E2s have been found and hundreds of E3s have been identified in humans.
    存储条件 Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
    关键字 UBC-9 | UBC 9 | P-18 | P 18

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    文献支持
    UBC9/UBE2I, Human, 重组蛋白
    ¥234 - 2197