- ￥95
- TargetMol
- T4497
- 2026年07月07日
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- 详细信息
- 文献和实验
- 技术资料
- CAS号：
54-96-6
- 规格：
1g/1mLx10mM(inDMSO)
| 规格： | 1g | 产品价格： | ￥95.0 |
|---|---|---|---|
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥95.0 |
Product Introduction
Bioactivity
| 名称 | Amifampridine |
| 描述 | Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is increased. Ca2+ channels can then be open for a longer time and allow greater acetylcholine release to stimulate muscle at the end plate. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | H2O : 24 mg/mL (219.92 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (18.33 mM), Sonication is recommended. DMSO : 60 mg/mL (549.8 mM), Sonication is recommended. |
| 关键字 | voltage-gated potassium | PotassiumChannel | Potassium Channel | Oral | neuromuscular junction | neurological disease | myasthenic syndrome | LEMS | KcsA | Inhibitor | inhibit | Amifampridine |
| 相关产品 | Chenodeoxycholic acid | Tannic acid | 2,2,2-Trichloroethanol | Minoxidil | Chlorzoxazone | Minoxidil sulfate | Tetraethylammonium bromide | 1,8-Cineole | Ursodeoxycholic acid | Indapamide | Taurocholic acid sodium salt hydrate | Hydrochlorothiazide |
| 相关库 | Bioactive Compound Library | Bioactive Compounds Library Max | Potassium Channel Targeted Library | EMA Approved Drug Library | Failed Clinical Trials Compound Library | FDA-Approved Drug Library | Ion Channel Targeted Library | Clinical Compound Library | Membrane Protein-targeted Compound Library | Orally Active Compound Library | Drug Repurposing Compound Library | Pain-Related Compound Library |
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文献和实验5.99 5.82 5.69 5.60 5.52 5.46 5.37 5.27 5.17 5.06 4.96 4.85 6 7 6.54 5.89 5.52 5.28 5.12 4.99 4.90 4.82 4.76 4.67 4.57 4.47 4.36 4.25 4.14 7 8 6.06 5.42 5.05 4.82 4.65 4.53 4.43 4.36 4.29 4.20 4.10 4.00 3.89 3.78 3.67 8 9 5.71 5.08 4.72 4.48
64、CD32、CD16、CD115、CD117、CDw121a、CDw121b、CD126、CDw130、CD2、CD4、CD7、CD8、CD19、CD28、CD31、CD48、CD50、CD54、CD58、CD66e、CD80、CDw90、CD96、CD102、CD106、CD56等。 （3）C表示粘附分子中属IGSF结构的分子，无CD编号，如MHCⅠ类和Ⅱ类分子。 （4）D表示CD命名范围中，具有粘附功能且属于IGSF结构
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