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- 技术资料
- CAS号：
514-36-3
- 规格：
1mLx10mM(inDMSO)/100mg/200mg
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥233.0 |
|---|---|---|---|
| 规格： | 100mg | 产品价格： | ￥213.0 |
| 规格： | 200mg | 产品价格： | ￥286.0 |
Product Introduction
Bioactivity
| 名称 | Fludrocortisone acetate |
| 描述 | Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of glucocorticoid-responsive genes such as lipocortins to inhibit phospholipase A2 (PLA2). Fludrocortisone acetate is the acetate salt of a synthetic fluorinated corticosteroid with anti-inflammatory and antiallergic activities. Inhibition of PLA2 activity prevents the release of arachidonic acid, a precursor of eicosanoids such as prostaglandins and leukotrienes; eicosanoids are important mediators in the pro-inflammatory response mechanism. As a mineralocorticoid-receptor agonist, this agent stimulates Na+ reabsorption and water retention and K+ and H+ secretion in the distal tubules and collecting ducts of the kidney. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | DMSO : 45 mg/mL (106.51 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (4.73 mM), Sonication is recommended. |
| 关键字 | Mineralocorticoid Receptor | Inhibitor | inhibit | GlucocorticoidReceptor | Glucocorticoid Receptor | Fludrocortisone Acetate | Fludrocortisone | Autophagy | 9α-fluorocortisol Acetate | 9α-Fluorcortisol Acetate | 9α-Fluorcortisol | 9α-Fludrocortisone Acetate | 9α-Fludrocortisone | 9alpha-fluorocortisol Acetate | 9alpha-Fluorcortisol Acetate | 9alpha-Fludrocortisone Acetate | 9a-fluorocortisol Acetate | 9a-Fluorcortisol Acetate | 9a-Fludrocortisone Acetate |
| 相关产品 | Guanidine hydrochloride | Naringin | Enzalutamide | Aceglutamide | Alginic acid | Cysteamine hydrochloride | Hemin | Hydroxychloroquine | Sildenafil citrate | Stavudine | Tamoxifen | Paeonol |
| 相关库 | Anti-Cancer Approved Drug Library | Bioactive Compound Library | Bioactive Compounds Library Max | Metabolism Compound Library | Anti-Aging Compound Library | Anti-COVID-19 Compound Library | FDA-Approved Drug Library | Immunology/Inflammation Compound Library | Drug Repurposing Compound Library | Anti-Cancer Clinical Compound Library | Anti-Cancer Drug Library | NMPA-Approved Drug Library |
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醋酸氟氢可的松【514-36-3】
￥213 - 286
