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- 技术资料
- CAS号:
40313-92-6
- 规格:
1mLx10mM(inDMSO)/1mg/5mg/10mg/25mg/50mg/100mg/200mg
| 规格: | 1mLx10mM(inDMSO) | 产品价格: | ¥872.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥436.0 |
| 规格: | 5mg | 产品价格: | ¥976.0 |
| 规格: | 10mg | 产品价格: | ¥1448.0 |
| 规格: | 25mg | 产品价格: | ¥2304.0 |
| 规格: | 50mg | 产品价格: | ¥3128.0 |
| 规格: | 100mg | 产品价格: | ¥4200.0 |
| 规格: | 200mg | 产品价格: | ¥5520.0 |
Product Introduction
Bioactivity
| 名称 | Thalidomide-5-methyl |
| 描述 | Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein. |
| 体外活性 | PROTACs通过连接器连接两种不同的配体;其中一个是E3泛素连接酶的配体,另一个则是目标蛋白的配体。PROTACs利用细胞内的泛素-蛋白酶体系统,选择性地降解目标蛋白[1]。 |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | DMSO : 50 mg/mL (183.65 mM), Sonication is recommended. |
| 关键字 | Thalidomide-5-methyl | Thalidomide5methyl | Thalidomide 5 methyl | Ligands for E3 Ligase | LigandforE3Ligase | Ligand for E3 Ligase | Inhibitor | inhibit | E3 ligase-recruiting Moiety |
| 相关产品 | Formamide | Urea | Guanidine hydrochloride | Naringin | Aceglutamide | Alginic acid | Metronidazole | Hemin | Hydroxychloroquine | Stavudine | Tamoxifen | Paeonol |
| 相关库 | Bioactive Compound Library | Bioactive Compounds Library Max |
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文献和实验Methyl DNA Immunoprecipitation
. The MBD method combined with enzymatic restriction of the DNA has been adapted to HTP (8 , 12 ). Yet another way to enrich for methylated DNA is by Methyl DNA IP. Methyl DNA IP uses bead-immobilized anti-5-methyl cytosine antibodies to isolate
”有什么区别呢? “纯度”一般指化合物的液相面积归一法测得面积百分比,即:杂质含量越少,该物质纯度越高。 “含量”是通过内标法、外标法、去水分法等测得的有效物质的质量百分含量。 A 一、 索莱宝·可溯源含量标准品: 精准到“权威机构”的信赖 可溯源含量标准品是指经过严格筛选、其特性值(如含量、浓度、理化性质等)可逐级追溯至现行有效的国家药品标准物质进行定值,这类标准品是分析检测中确保数据准确性和可比性的核心载体,有具体的含量定值,广泛应用于药品研发、环境监测、食品检测、仪器校准及法规符合
Crystallization of Kinesin Family Motor Proteins
.,2001; Nitta et al.,2004); the Kinesin-5 (formerly BimC)motor,monomeric Eg5 (Turner et al.,2001); and the Kinesin-13 (formerly MCAK)motor,PfKinI (Shipley et al.,2004).The following tables summarize the crystallization conditions and some of the crystal
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