- ￥122 - 1272
- TargetMol
- T17879
- 2026年07月07日
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- CAS号：
1225383-33-4
- 规格：
5mg/10mg/25mg/50mg/100mg/200mg
| 规格： | 5mg | 产品价格： | ￥122.0 |
|---|---|---|---|
| 规格： | 10mg | 产品价格： | ￥183.0 |
| 规格： | 25mg | 产品价格： | ￥330.0 |
| 规格： | 50mg | 产品价格： | ￥548.0 |
| 规格： | 100mg | 产品价格： | ￥872.0 |
| 规格： | 200mg | 产品价格： | ￥1272.0 |
Product Introduction
Bioactivity
| 名称 | E3 ligase Ligand 8 |
| 描述 | E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. The E3 ligase Ligand 8 can be linked to protein ligands through linkers to form PROTACs, which are inducers of ubiquitination-mediated degradation of cancer-promoting proteins. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | DMSO : 90 mg/mL (169.62 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (6.22 mM), Sonication is recommended. |
| 关键字 | Ligands for E3 Ligase | LigandforE3Ligase | Ligand for E3 Ligase | Inhibitor | inhibit | E3 ligase-recruiting Moiety | E-3 ligase Ligand 8 | E3 ligase Ligand 8 |
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文献和实验Reconstitution of CHIP E3 Ubiquitin Ligase Activity
CHIP, the carboxyl-terminus of Hsp70 interacting protein, is both an E3 ubiquitin ligase and an Hsp70 co-chaperone and is implicated in the degradation of cytosolic quality control and numerous disease substrates. CHIP has been shown
Purification and Characterization of Legionella U-Box-Type E3 Ubiquitin Ligase
Bacterial virulence proteins often mimic host eukaryotic proteins to modify or disturb host cellular �pathways. Increasing lines of evidence show that many bacterial effector proteins have E3 ubiquitin ligase activity. The effector protein
近期，来自广西大学动物科技学院的李一星教授和广西壮族自治区人民医院的周磊教授团队在 Imeta 杂志发表了题为「HLF and PPARα axis regulates metabolic‐associated fatty liver disease through extracellular vesicles derived from the intestinal microbiota」的科研论文，IF = 33.2。 研究背景： 代谢相关性脂肪肝（Metabolic
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