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- 2026年07月07日
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5μg/10μg/20μg/50μg
| 规格： | 5μg | 产品价格： | ￥469.0 |
|---|---|---|---|
| 规格： | 10μg | 产品价格： | ￥743.0 |
| 规格： | 20μg | 产品价格： | ￥1183.0 |
| 规格： | 50μg | 产品价格： | ￥2117.0 |
Product Introduction
Bioactivity
| 名称 | AKT1 Protein, Human, Recombinant (His) |
| 描述 | v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to insulin, insulin-like growth factor 1 (IGF1), and glucose. AKT1 also plays a key role in the regulation of both muscle cell hypertrophy and atrophy. AKT1 activity is required for physiologic cardiac growth in response to IGF1 stimulation or exercise training. In contrast, AKT1 activity was found to antagonize pathologic cardiac growth that occurs in response to endothelin 1 stimulation or pressure overload. AKT1 selectively promotes physiological cardiac growth while AKT2 selectively promotes insulin-stimulated cardiac glucose metabolism. AKT1 deletion prevented tumor initiation as well as tumor progression, coincident with decreased Akt signaling in tumor tissues. AKT1 is the primary Akt isoform activated by mutant K-ras in lung tumors, and that AKT3 may oppose AKT1 in lung tumorigenesis and lung tumor progression. A number of separate studies have implicated AKT1 as an inhibitor of breast epithelial cell motility and invasion. AKT1 may have a dual role in tumorigenesis, acting not only pro-oncogenically by suppressing apoptosis but also anti-oncogenically by suppressing invasion and metastasis.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 存储条件 | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
| 关键字 | CWS-6 | CWS 6 |
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文献和实验摘要 Groundbreaking work demonstrated that ectopic expression of four transcription factors, Oct4, Klf4, Sox2, and c-Myc, could reprogram murine somatic cells to induced pluripotent stem cells (iPSCs) (Takahashi and Yamanaka, 2006), and human
BioSpectrum Asia：从米粒生产重组蛋白用于工业和医学
as a postdoctoral researcher at the Institute of Molecular Agrobiology, National University of Singapore. Human serum albumin (HSA) is a soluble protein that functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones, and plays
我们知道，PeproTech的所有细胞因子和蛋白均为冻干粉，这使得运输非常便捷，只要常温即可。而且，细胞因子和蛋白冻干粉非常稳定，在-20℃或-80℃条件下可保存数年。冻干粉在使用前需进行溶解，然后以液体形式加到培养体系或注射入动物体内。溶解步骤非常关键，因溶解不好会导致细胞因子或蛋白的失活，这也是很多用户在实际使用中经常遇到的问题。 那么，应该如何进行正确的溶解呢？ 下面我们以Recombinant Human IL-4 (重组人IL-4，产品编号：200-04)的说明书为例
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