- ￥197 - 3744
- TargetMol
- T3715
- 2026年07月07日
2 年钻石会员
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- CAS号：
943764-99-6
- 规格：
1mg/1mLx10mM(inDMSO)/5mg/10mg/25mg/50mg/100mg/200mg
| 规格： | 1mg | 产品价格： | ￥197.0 |
|---|---|---|---|
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥472.0 |
| 规格： | 5mg | 产品价格： | ￥421.0 |
| 规格： | 10mg | 产品价格： | ￥580.0 |
| 规格： | 25mg | 产品价格： | ￥1176.0 |
| 规格： | 50mg | 产品价格： | ￥1880.0 |
| 规格： | 100mg | 产品价格： | ￥2696.0 |
| 规格： | 200mg | 产品价格： | ￥3744.0 |
Product Introduction
Bioactivity
| 名称 | Acebilustat |
| 描述 | Acebilustat (CTX-4430) (ZK322) is an effective and specific leukotriene B4 hydrolase inhibitor. |
| 激酶实验 | Rolapitant is made at a stock concentration of 1 mM in 100% DMSO. For most receptor binding studies, the stock solution is diluted with the final concentrations ranged from 0.1 to 3 μM. Radioligand concentrations for competition binding studies ranged from 0.5 to 1 nM. For species comparison studies, 150 pM [125I]-BHSP is incubated with varying concentrations of protein (10-50 μg) prepared from gerbil, rabbit and monkey striata, and from cells expressing cloned rat, mouse and guinea pig NK receptors[1]. |
| 体外活性 | Acebilustat是一种白三烯A4水解酶抑制剂，其在第一阶段试验中被证明是安全且耐受性良好[1]。Acebilustat作为一种抗炎化合物，正在开发中，用于治疗囊性纤维化(CF)及其他疾病。它是一个强效的白三烯A4水解酶(LTA4H)抑制剂，该酶催化生成白三烯B4(LTB4)的速率限制步骤，LTB4是一种强效的趋化因子和炎症免疫细胞（包括中性粒细胞）的激活剂[2]。 |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | DMSO : 60 mg/mL (124.6 mM), Sonication is recommended. Methanol : 32 mg/mL (66.45 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (2.08 mM), Sonication is recommended. |
| 关键字 | LTB4 | Inhibitor | inhibit | CTX4430 | CTX 4430 | Aminopeptidase | Acebilustat |
| 相关产品 | Tebufelone | Bestatin | Montelukast sodium | Tosedostat | Bestatin hydrochloride | Pranlukast | SC-22716 | Bufexamac | L(+)-Leucinol | LTβR-IN-1 | Ticolubant | Betulinic acid |
| 相关库 | Inhibitor Library | Bioactive Compound Library | Bioactive Compounds Library Max | Metabolism Compound Library | ReFRAME Related Library | Coagulation and Anticoagulation Compound Library | Anti-Fibrosis Compound Library | Nonsteroidal Anti-Inflammatory Compound Library | NO PAINS Compound Library | Immunology/Inflammation Compound Library | Drug Repurposing Compound Library | Target-Focused Phenotypic Screening Library |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
官网有文献
技术资料暂无技术资料 索取技术资料
文献支持
阿西鲁司特【943764-99-6】
￥197 - 3744
