- ￥329 - 1320
- TargetMol
- T36292
- 2026年07月07日
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- 文献和实验
- 技术资料
- CAS号：
102586-30-1
- 规格：
1mg/5mg/10mg
| 规格： | 1mg | 产品价格： | ￥329.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥794.0 |
| 规格： | 10mg | 产品价格： | ￥1320.0 |
Product Introduction
Bioactivity
| 名称 | NSC 12 |
| 描述 | NSC 12 is an orally active pan-FGF trap that inhibits FGF-dependent tumor cell proliferation, angiogenesis, and metastasis.NSC 12 binds FGF2 and interferes with its interaction with FGFR1, but does not affect the ability of FGF2 to bind heparin or heparan sulfate proteoglycans (HSPGs), with potential antitumor activity.NSC 12 also organizes several other FGF isoforms to form the HSPG/FGF/FGFR ternary complex. |
| 存储条件 | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | Ethanol:PBS (pH 7.2)(1:2) : Insoluble, < 0.1 mg/mL (insoluble) DMSO : 8 mg/mL (16.51 mM), Sonication is recommended. Ethanol : 8 mg/mL (16.51 mM), Sonication is recommended. DMF : 8 mg/mL (16.51 mM), Sonication is recommended. |
| 关键字 | NSC-12 | NSC 12 |
| 相关产品 | Amlexanox | Lenvatinib | Formononetin | Lenvatinib mesylate | Ferulic Acid | Regorafenib | Pazopanib | Nintedanib | Pemigatinib | Erdafitinib | Regorafenib monohydrate | Nintedanib esylate |
| 相关库 | Anti-Cancer Active Compound Library | Bioactive Compound Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Bioactive Lipid Compound Library | Kinase Inhibitor Library | Fluorochemical Library | Anti-Lung Cancer Compound Library | Tyrosine Kinase Inhibitor Library | Post-Translational Modification Compound Library |
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文献和实验Neurosphere and Neural Colony-Forming Cell Assays
), neural stem cells (NSC) are often isolated and studied using a culture system referred to as the neurosphere assay. Since its introduction in 1992, the neurosphere system has been used to isolate, expand, and identify the presence of an NSC population
定群研究 提要定群研究的概念及设计原理；研究方法（暴露组选择、对照组选择）；样本含量估计；资料来源和收集，资料分析；人年计算、率的计算、相对危险度、特异危险度、人群特异危险度；定群研究中常见的偏倚。 案例英国Harold对风疹与先天性畸形关系进行了研究。研究对象为1956年初到1957年12月在英格兰和威尔士的孕妇，曾患风疹的孕妇共578例，列为暴露组，从未患过风疹的孕妇中随机抽取2%样本作为非暴露组共5717人。追踪观察她们所生的婴儿直至2岁
Methods for Analysis of Brain Tumor Stem Cell and Neural Stem Cell Self-Renewal
Neural stem cells (NSC) self-renew and are multipotent, producing neurons and glia. Recent studies have shown that brain tumors (BT) contain cells that, like NSC, self-renew and are multipotent, producing the different types of cells
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