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- 2026年07月07日
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1mLx10mM(inDMSO)/2mg/5mg/10mg/25mg/50mg/100mg/200mg
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥215.0 |
|---|---|---|---|
| 规格： | 2mg | 产品价格： | ￥88.0 |
| 规格： | 5mg | 产品价格： | ￥134.0 |
| 规格： | 10mg | 产品价格： | ￥188.0 |
| 规格： | 25mg | 产品价格： | ￥261.0 |
| 规格： | 50mg | 产品价格： | ￥267.0 |
| 规格： | 100mg | 产品价格： | ￥364.0 |
| 规格： | 200mg | 产品价格： | ￥532.0 |
Product Introduction
Bioactivity
| 名称 | Beta-Sheet Breaker Peptide iAβ5 Acetate |
| 描述 | Beta-Sheet Breaker Peptide iAβ5 Acetate (C33H43N5O8) inhibit amyloidogenesis in rat brain models. |
| 体内活性 | 该5-residue peptide能够抑制amyloid beta-protein的纤维生成，在体外分解已形成的纤维，并防止细胞培养中纤维引起的神经元死亡。此外，beta-sheet breaker peptide在体内显著减少amyloid beta-protein沉积，并在一种amyloidosis的大鼠脑模型中完全阻断amyloid fibrils的形成。这些发现可能为预防Alzheimer's病中amyloidosis提供一种新的治疗方法的基础。 |
| 存储条件 | Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | DMSO : 60 mg/mL (85.99 mM), Sonication is recommended. |
| 关键字 | β-Sheet Breaker Peptide iAβ5 Acetate | b-Sheet Breaker Peptide iAb5 Acetate | Beta-Sheet Breaker Peptide iAβ5 Acetate | BetaSheet Breaker Peptide iAβ5 Acetate | Beta-Sheet Breaker Peptide iAbeta5 Acetate | Beta-Sheet Breaker Peptide iAb5 Acetate | Beta Sheet Breaker Peptide iAβ5 Acetate |
| 相关库 | Inhibitor Library | Bioactive Compound Library | Bioactive Compounds Library Max | Peptide Compound Library | NO PAINS Compound Library |
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文献和实验Assembly of Matched Alpha/Beta Subunits to HLA Class II Peptide Receptors
on the same chromosome) or trans (encoded on different chromosomes) combinations. Since some of the α–β combinations may yield mismatched non-functional α–β heterodimers, it is not entirely clear which type of HLA class II peptide receptors are found on the cell surface
and Turns of β-Peptides with Proteinogenic Side Chains. Angew. Chem. Int. Ed., 1999, 38: 1595. b) Krauth?user S, Christianson LA, Powell DR, Gellman SH. Antiparallel Sheet Formation in β-Peptide Foldamers: Effects of β-Amino Acid Substitution
Microwave-Assisted Solid-Phase Peptide Synthesis Using the Biotage Syro Wave
has proven to be a useful and reliable tool for the synthesis of peptides as well as small proteins. It is particularly well suited for sequences with a high propensity to form β-sheet-type structures and for sterically difficult couplings. In this protocol
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