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- 技术资料
- CAS号：
751475-53-3
- 规格：
1mLx10mM(inDMSO)/1mg/2mg/5mg/10mg/25mg/50mg/100mg
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥1368.0 |
|---|---|---|---|
| 规格： | 1mg | 产品价格： | ￥432.0 |
| 规格： | 2mg | 产品价格： | ￥660.0 |
| 规格： | 5mg | 产品价格： | ￥1176.0 |
| 规格： | 10mg | 产品价格： | ￥2048.0 |
| 规格： | 25mg | 产品价格： | ￥3336.0 |
| 规格： | 50mg | 产品价格： | ￥4744.0 |
| 规格： | 100mg | 产品价格： | ￥6264.0 |
Product Introduction
Bioactivity
| 名称 | Atopaxar |
| 描述 | Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome. |
| 激酶实验 | Kinase assays: WHI-P154 is tested in kinase assays. The panel of kinases is selected to broadly cover the kinome, providing a good approximation of specificity. For all kinases, recombinant rat (IKKβ) or human (all others), full-length or GST-kinase domain fusion proteins, are used. WHI-P154 is inactive (concentration that inhibits response by 50% [IC50] > 30 μM) for the following kinases: AKT, AuroraA, cdk2, cdk6, CHK1, FGFR1, GSK3b, IKKb, IKKi, INSR, MAPK1, MAPKAP-K2, MASK, MET, PAK4, PDK1, PKCb, ROCK1, TaoK3, TrkA. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | DMSO : 30 mg/mL (56.86 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.79 mM), Sonication is recommended. |
| 关键字 | Thrombin receptors | thrombin | signaling | receptor-1 | receptor | ProteaseactivatedReceptor | Protease-Activated Receptor (PAR) | Proteaseactivated Receptor | protease-activated | Protease Activated Receptor (PAR) | platelets | PAR-1 | Inhibitor | inhibit | E-5555 | E 5555 | Atopaxar | atherothrombotic |
| 相关产品 | Formamide | Urea | Sodium Molybdate | Dimethyl phthalate | Aceglutamide | Alginic acid | Cysteamine hydrochloride | Metronidazole | Sildenafil citrate | Citric Acid Triammonium | Stavudine | Tamoxifen |
| 相关库 | Inhibitor Library | Bioactive Compound Library | Bioactive Compounds Library Max | Kinase Inhibitor Library | Fluorochemical Library | GPCR Compound Library | Immunology/Inflammation Compound Library | Membrane Protein-targeted Compound Library | Tyrosine Kinase Inhibitor Library | Drug Repurposing Compound Library | Anti-Cancer Clinical Compound Library | Anti-Cancer Drug Library |
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￥432 - 6264
