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- CAS号:
289893-25-0
- 规格:
1mg/1mLx10mM(inDMSO)/5mg/10mg/25mg/50mg/100mg
| 规格: | 1mg | 产品价格: | ¥253.0 |
|---|---|---|---|
| 规格: | 1mLx10mM(inDMSO) | 产品价格: | ¥614.0 |
| 规格: | 5mg | 产品价格: | ¥582.0 |
| 规格: | 10mg | 产品价格: | ¥872.0 |
| 规格: | 25mg | 产品价格: | ¥1464.0 |
| 规格: | 50mg | 产品价格: | ¥2184.0 |
| 规格: | 100mg | 产品价格: | ¥3192.0 |
Product Introduction
Bioactivity
| 名称 | Arimoclomol |
| 描述 | Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS). |
| 体内活性 | In male Wistar rats, Arimoclomol (20 mg/kg; gavage) protects cholecystokinin-octapeptide (CCK)-induced acute pancreatitis. The pancreatic levels of HSP60 and HSP72 are significantly increased[2]. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | DMSO : 150 mg/mL (478.04 mM), Sonication is recommended. |
| 关键字 | ubiquitin | system | protein | proteasome | neurons | motor | misfolded | Inhibitor | inhibit | HSP | Heat shock proteins | co-inducer | clearance | BRX-220 | BRX220 | BRX 220 | assemblies | Arimoclomol | aggregation |
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| 相关库 | Bioactive Compound Library | Bioactive Compounds Library Max | Metabolism Compound Library | ReFRAME Related Library | Failed Clinical Trials Compound Library | FDA-Approved & Pharmacopeia Drug Library | Cytoskeletal Signaling Pathway Compound Library | Approved Drug Library | FDA-Approved Drug Library | Clinical Compound Library | Membrane Protein-targeted Compound Library | Drug Repurposing Compound Library |
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(tedelparin),弗希肝素(fraxiparin),洛吉肝素(logiparin),洛莫肝素(lomoparin)等。 香豆素类 Coumarin 【化学结构】 香豆素类药有华法林(warfarin,苄丙酮香豆素)、双香豆素(dicoumarol)、醋硝香豆素(acenocoumarol,新抗凝)。它们均具有4-羟基香豆素(4-hydroxycoumarin)的基本结构,这类药口服有效,故又称口服抗凝血药。 【药理作用与机制】 本类药物是vitamin
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¥253 - 3192









