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- 文献和实验
- 技术资料
- 供应商:
武汉研升生物科有限公司
- 检测范围:
0.32-20 ng/mL
- 检测方法:
Sandwich
- 适应物种:
Human
- 样本:
Serum, plasma, tissue homogenates and other biological fluids.
- 灵敏度:
0.109 ng/mL
- 规格:
48T/96T
| 规格: | 48T | 产品价格: | ¥1820.0 |
|---|---|---|---|
| 规格: | 96T | 产品价格: | ¥2600.0 |
| 中文名称 | 人Toll样受体8(TLR8)酶联免疫吸附检测试剂盒 |
| 英文名称 | Human TLR8(Toll Like Receptor 8) ELISA Kit |
| 别名 | CD288 |
| 货号 | ELK2737 |
| 反应种属 | Human |
| Q9NR97 | Q9NR97 |
| 检测类型 | Sandwich |
| 灵敏度 | 0.109 ng/mL |
| 标准品 | 20 ng/mL |
| 检测范围 | 0.32-20 ng/mL |
| 样本类型 | Serum, plasma, tissue homogenates and other biological fluids. |
| 反应时间 | 3.5h |
| 检测原理 | The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TLR8. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TLR8. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human TLR8, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human TLR8 in the samples is then determined by comparing the OD of the samples to the standard curve. |
| 研究领域 | Signal transduction;Tumor immunity;Infection immunity;Immune molecule;Pulmonology; |

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文献和实验治疗靶点 来源:Toll-like receptor 8 is a therapeutic target in rheumatoid arthritis.Arthritis Rheumatol,2026 Apr 13 图源:10.1002/art.70175[5] 清华大学尹航课题组联合协和医院、北京拓领博泰生物科技有限公司在风湿病学国际期刊Arthritis & Rheumatology发表研究,发现Toll样受体8(TLR8)是类风湿性关节炎(RA)的关键药物靶点。类风湿性关节炎是高发
Development of TLR7/8 Small RNA Antagonists
Toll-like receptors (TLRs) expressed by innate immune cells recognize a spectrum of microbial structures. Recent studies have provided convincing evidence that TLR7 and TLR8 play a key role in sensing viral RNAs. Under certain conditions
章)。后者又称为内吞型PRR,有甘露糖受体、清道夫受体(SR)、N-甲酰甲硫氨酰受体、Toll样受体(TLR)、NLR受体等。甘露糖受体可特异性识别并结合微生物细胞壁糖蛋白和糖脂组分中的末端甘露糖和岩藻糖残基,从而介导Mφ的吞噬作用;SR可与细菌细胞壁的某些组分结合,有效地清除血循环中的细菌;TLR是一类跨膜受体,通过识别并结合相应PAMP,可启动激活信号转导途径,并诱导某些免疫分子(包括炎性细胞因子)表达。 已发现TLR有11种,TLRl、TLR2、TLR4、TLR5、TLR
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