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- 文献和实验
- 技术资料
- 亚型:
Fusion - [ACVR2A (activin A receptor type 2A, ActR-II, ActRIIA)]2 - IGHG1 Fc (Fragment constant)
- 形态:
Liquid
- 保存条件:
-20°C
- 适应物种:
Human
- 保质期:
12 months
- 级别:
一抗
- 供应商:
武汉研升生物科技有限公司
- 应用范围:
ELISA, Functional assay, Research in vivo
- 抗体英文名:
Research Grade Sotatercept
- 规格:
100μg/1mg
| 规格: | 100μg | 产品价格: | ¥2968.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥8888.0 |
| 产品名 | Research Grade Sotatercept |
| 货号 | HY428026 |
| 别名 | ACE-011, ACTRIIA-Fc, MK7962, MK-7962, MK7962, Sotatercept(USAN/INN), SOTATERCEPT-CSRK, WINREVAIR, 1001080-50-7 |
| 表达系统 | Mammalian Cells |
| 靶标 | EDF, Erythroid differentiation protein, Activin beta-A chain, INHBA, Inhibin beta A chain |
| Accession号 | P08476 |
| 种属反应性 | Human |
| 同种型 | Fusion - [ACVR2A (activin A receptor type 2A, ActR-II, ActRIIA)]2 - IGHG1 Fc (Fragment constant) |
| 内毒素水平 | Please contact the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 应用 | ELISA, Functional assay, Research in vivo |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 状态 | Liquid |
| 背景 | Sotatercept (ACE-011) is a soluble activin receptor 2A (ACVR2A) type IgG Fc fusion protein. Sotatercept combines activin and growth differentiation factor to try to restore the balance between growth promotion and growth inhibition signal pathways. Sotatercept has potential application in pulmonary arterial hypertension, anemia, bone loss, erythropoiesis, multiple myeloma (MM) osteolytic lesions. |
| 保存溶液 | 0.01M PBS, pH 7.4. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 说明 | For research use only. Not suitable for clinical or therapeutic use. |

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