- $495
- Leading Biology
- United States
- APR08857G
- 2026年03月31日
- Rabbit
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
64-92 aa
- 亚型：
Rabbit Ig
- 保存条件：
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 库存：
100
- 宿主：
Rabbit
- 靶点：
This OLR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human OLR1.
- 抗体名：
CLEC8A, LOX1
- 规格：
100 μl
30959 Da
细胞定位：
Antigen Cellular Localization: Cell membrane; Lipid-anchor. Cell membrane; Single-pass type II membrane protein. Membrane raft. Secreted Note=A secreted form also exists. Localization to membrane rafts requires palmitoylation
形式：
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献：
Predazzi,I.M.,et.al., Ann. Hum. Biol. 37 (2), 136-148 (2010)
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality OLR1 antibody (Center).
功能：
Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro- oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro- atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram- positive bacteria.
总结：
OLR1 is a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor.
联系方式：
生物商城：http://www.annoron.com
办公电话：010-56256916
官方售后：400-965-8633
企业 QQ：3212874516、3198592576
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文献和实验Double immunohistochemistry for BCL6 and PNA for Germinal Center detection.
(see Reagents and Solutions). 3- incubate with the blocking for 10 min. If one of your antibody is biotin-conjugated, you need at this point to do endogenous biotin blocking. 4- blot the slides without washing and apply the primary antibody, in a moist
Double immunohistochemistry for BCL6 and PNA for Germinal Center detection
Double immunohistochemistry for BCL6 and PNA for Germinal Center detection. (on fixed, paraffin-embedded sections) Cut sections at 4µm, use a clean water bath with distilled water, and let the sections dry
with those with a postgerminal center/activated profile. Microarray technology may not be available in many diagnostic laboratories, and antibody-based methods are much simpler and cheaper and are therefore more applicable to the routine setting. Immunocytochemistry
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