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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
参照说明书
- 英文名:
Ouabain (OB) Protein (OVA)
- 库存:
1
- 供应商:
北京博蕾德生物科技有限公司
- 规格:
10 μg///50 μg///100 μg
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文献和实验Proteomic Analysis of Vascular Smooth Muscle Cells Treated With Ouabain
, we identified mortalin (also known as GRP75 or PBP-74), a member of the heat shock protein 70 superfamily and a marker for cellular mortal and immortal phenotypes. Further experiments showed that mortalin RNA and protein levels are induced in ouabain-treated
Cell Metab:北大邱义福团队发现「产热通道」介导的褐色脂肪产热新机制
肥胖已成为全球性的重大健康问题,在个体层面可以通过增加能量消耗来对抗肥胖。自 2009 年在成人中检测到代谢活跃的褐色/米色脂肪组织(BAT (brown adipose tissue) or beige fat)以来,科学家们一直在寻找增强褐色/米色脂肪产热从而增加能量消耗、抵抗肥胖的方法。 褐色脂肪组织线粒体富含解偶联蛋白 UCP1(uncoupling protein 1)。UCP1 能够提高线粒体内膜对质子的电导性,从而消耗质子梯度,将氧化磷酸化与 ATP 合成解偶联,把底物氧
were from Novex (San Diego, CA, USA). To the analytical 2-D gels 25 _g protein was loaded corresponding to approx. 20 mg wet adipose tissue. Liver tissue from ob/ob mice were homogenised in the same manner and in the same buffer (9 M urea, 30 mM DTT, and 0.5% IPG
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