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参照说明书
- 英文名:
MAD2 Mitotic Arrest Deficient-Like 1 Protein
- 库存:
1
- 供应商:
北京博蕾德生物科技有限公司
- 规格:
1 μg///5 μg///50 μg
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文献和实验Microtubule inhibitors such as Vinblastine and Paclitaxel are chemotherapy agents that activate the mitotic spindle checkpoint, arresting cells in mitosis and leading to cell death. The pathways that connect mitotic arrest to cell death
The p53 protein (reviewed in refs. 1 –5 ) is a latent transcription factor that is activated in response to a variety of cellular stresses, including DNA damage, mitotic spindle damage, heat shock, hypoxia, cytokines, metabolic changes
Analysis of the Spindle-Assembly Checkpoint in HeLa Cells
The spindle-assembly checkpoint involves signaling at kinetochores, which leads to the arrest of mitotic progression in the absence of microtubule attachment or spindle tension. Here, we detail procedures for the analysis of the spindle
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