- ￥180 - 400
- Elabscience
- 武汉
- AN009640P
- 2026年03月11日
- FCM
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
Mouse IgG1, κ
- 形态：
液体
- 保存条件：
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
12个月
- 级别：
科研级别
- 库存：
99
- 供应商：
Elabscience
- 宿主：
Mouse
- 应用范围：
FCM
- 靶点：
CD178
- 抗体英文名：
Purified Anti-Human CD178 Antibody[NOK-1]
- 抗体名：
CD178抗体
- 规格：
100μg/25μg
| 规格： | 100μg | 产品价格： | ￥400.0 |
|---|---|---|---|
| 规格： | 25μg | 产品价格： | ￥180.0 |
Purified Anti-Human CD178 Antibody[NOK-1]
| Alternate Names |
Apoptosis (APO 1) antigen ligand 1, Apoptosis antigen ligand 1, CD95 ligand, CD95L protein, Fas L, Fas ligand (TNF superfamily member 6), Fasl Fas ligand (TNF superfamily member 6), Generalized lymphoproliferative disease, Gld, soluble form, TNFL6, Tumor necrosis factor (ligand) superfamily member 6, apoptosis(APO-1) antigen ligand, apoptosis (APO-1) antigen ligand, tumor necrosis factor ligand superfamily member, TNFSF, APT1LG, FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6, TNLG1A, Fas ligand, Apo I Ligand, apoptosis (APO-1) antigen ligand 1, Fas ligand (TNF superfamily, member 6), soluble Fas Ligand (sFasL), APT1LG1CD95L, TNFSF6FasL, apoptosis(APO-1) antigen ligand 1, Apoptosis antigen ligand, CD178 antigen, Fas antigen ligand, FASLCD95 ligand, tumor necrosis factor ligand superfamily member 6, CD95L, TNFSF6
|
| Cellular Localization |
Cell membrane, Secreted
|
| Clone No |
NOK-1
|
| Isotype |
Mouse IgG1, κ
|
| Verified Samples | Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Human CD178 gene |
| Dilution |
FCM 2 μg/mL(0.5×106-1×106 cells)
|
| Background |
Fas Ligand (FasL), also known as CD178, CD95L, or TNFSF6, is a transmembrane protein homotrimer that binds to Fas/CD95 and triggers apoptosis in the Fas-expressing cell. Fas Ligand also binds the soluble decoy receptor DcR3. It is expressed on activated Th1 cells, CD8+ cytotoxic T cells, and NK cells. A soluble form can be released which remains trimeric and retains the ability to bind Fas. Fas Ligand-induced apoptosis plays a central role in the development of immune tolerance and the maintance of immune privileged sites. Tumor cells can evade immune surveillance by upregulating Fas Ligand to kill tumor infiltrating lymphocytes. In gld mice, a Fas Ligand point mutation is the cause of severe lymphoproliferation and systemic autoimmunity.
|
| Immunogen | Recombinant Human CD178 protein |
| Abbre |
CD178
|
| Swissprot |
P48023
|
| Host |
Mouse
|
| Reactivity |
Human
|
| Clonality |
Monoclonal
|
| Purification Method |
>98%, Protein A/G purified
|
| Applications |
FCM
|
| Research Areas | Stem Cells;Immunology;Cell Biology;Cytokine and Growth Factors;Mitochondrial Pathway;Death Receptors Signaling Pathway;CDs;Hematopoietic Stem Cell Markers |
| Concentration |
≥ 1 mg/mL
|
| Conjugation |
Unconjugated
|
| Storage Buffer |
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
|
| Storage |
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
|
| Expiration Date |
12个月
|
| Shipping |
Ice bag
|
Purified Anti-Human CD178 Antibody[NOK-1]Elabscience®流式抗体致力于为您的流式细胞分析实验带来更优质的体验，已有3,000+指标，选用经典克隆株纯化抗体，产品涵盖抗人/大鼠/小鼠等，指标丰富。
Purified Anti-Human CD178 Antibody[NOK-1] 4°C 保存，保质期 12 个月；或于 -20°C 保存（适合长期保存），避免反复冷冻/解冻。
Purified Anti-Human CD178 Antibody[NOK-1]产品更多产品信息查看欢迎咨询我们和搜索武汉伊莱瑞特Elabscience官网查看。
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文献和实验a simple ELISA method to detect human anti-antibody response.
Purification of Immature CD4+CD8+ Thymocytes by Panning with Anti-CD8 Antibody
Most T lymphocytes of the immune system differentiate within the thymus along the CD4/CD8 developmental pathway by a highly ordered process termed thymic selection ( 1 , 2 ). The maturation status of thymocytes is commonly assessed
Purification Of Anti Peptide Antibody
antibody that could contribute to staining background. The proportion in each pool varies with the peptide immunogen. The quality of the anti-peptide serum seems to increase with multiple boosts - the first bleed may be feeble.
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